Disease: Inflammatory disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XIAP P98170 X-linked inhibitor of apoptosis Enzyme modulator 0.92 0.447 0.808
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846
XBP1 P17861 X-box binding protein 1 3.2E-02 0.477 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TREM1 Q9NP99 triggering receptor expressed on myeloid cells 1 6.3E-03 0.515 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
THAS thoracoabdominal syndrome 0.560 0.808
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
S100A8 P05109 S100 calcium binding protein A8 Calcium-binding protein 0.14 0.430 0.962
PTPN2 P17706 protein tyrosine phosphatase non-receptor type 2 1.00 0.538 0.692
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PSC Cholangitis, primary sclerosing 0.603 0.731
PRTN3 P24158 proteinase 3 Enzyme 3.8E-05 0.503 0.808
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
MYLK Q15746 myosin light chain kinase Kinase 9.2E-12 0.510 0.846